Translink has closed the railway line between Belfast and Dublin until further notice.
Inspector Gary Jones said police had been made aware of suspicious activity in the area of the Bells Row crossing in the vicinity of Antrim Road, Lurgan.
The Antrim Road and Cornakinnegar Roads are closed at the railway crossing point.
Translink is running substitute bus services between Lurgan, Moira, Portadown and Lisburn.
There are no further details at this stage.
Deputy Mayor of Craigavon, Sinn Féin’s Catherine Seeley, has said those responsible for “another bomb scare on the railway lines close to Lurgan should come forward and explain themselves”.
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